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| BIO 512 | Metabolism | 3+0+0 | ECTS:7.5 | | Year / Semester | Spring Semester | | Level of Course | Second Cycle | | Status | Elective | | Department | DEPARTMENT of MEDICAL BIOLOGY | | Prerequisites and co-requisites | None | | Mode of Delivery | Face to face | | Contact Hours | 14 weeks - 3 hours of lectures per week | | Lecturer | -- | | Co-Lecturer | None | | Language of instruction | Turkish | | Professional practise ( internship ) | None | | | | The aim of the course: | | The course aims to provide the students with a general knowledge on basic metabolic pathways, their enzymes and regulation. |
| Programme Outcomes | CTPO | TOA | | Upon successful completion of the course, the students will be able to : | | | | PO - 1 : | Discuss about the basic aspects and regulation of metabolism | 1,2 | 1,3 | | PO - 2 : | Explain carbohydrate metabolism together with their enzymes | 1,2 | 1,3 | | PO - 3 : | Summarize lipid and amino acid metabolism together with their enzymes | 1,2 | 1,3 | | PO - 4 : | Discuss about the integration of fuel metabolism together with starvation state | 1,2 | 1,3 | | CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), PO : Learning Outcome | | |
| Glycolysis, Gluconeogenesis, Pentose phosphate pathway, Metabolic regulation, The Citric acid cycle, Electron transport system, Lipid Metabolism, Amino acid and nucleotide metabolism, Metabolic integration |
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| Course Syllabus | | Week | Subject | Related Notes / Files | | Week 1 | Digestion, absrbtion and transport of carbohydrates | | | Week 2 | Anaerobic and aerobic glycolysis
Metabolism of non-glucose carbohydrates | | | Week 3 | Citric acid cycle and metabolic importance | | | Week 4 | Pentose phosphate pathway and metabolic importance | | | Week 5 | Gluconeogenesis | | | Week 6 | Glycogenesis and glycogenolysis
Regulation of carbohydrate metabolism | | | Week 7 | Digestion and absorbtion of lipids and lipoproteins | | | Week 8 | Mid-term exam | | | Week 9 | Oxidaton of fatty acids and ketone bodies | | | Week 10 | Synthesis of fatty acids and regulation of fatty acid metabolism | | | Week 11 | Syhthesis of triacylglycerols, phospholipids and cholesterol | | | Week 12 | Digestion of proteins and absorbtion, transport and catabolism of amino acids, urea cycle | | | Week 13 | Synthesis of amino acids and nitrogen containing biomolecules, porphyrin and purine-pyrimidine metabolism | | | Week 14 | Metabolic integration
Regulation of blood glucose level and fasting metabolism | | | Week 16 | Final exam | | | |
| 1 | Prof. Dr. E. Edip Keha ve Prof. Dr. Ö. İrfan Küfrevioğlu, 2009, "Biyokimya", 5.baskı, Aktif Yayınevi, İstanbul | | | 2 | Prof. Dr. E. Edip Keha'nın ders notları | | | |
| Method of Assessment | | Type of assessment | Week No | Date | Duration (hours) | Weight (%) | | Mid-term exam | 8 | | 2 | 30 | | Homework/Assignment/Term-paper | 11 | | 3 | 20 | | End-of-term exam | 16 | | 2 | 50 | | |
| Student Work Load and its Distribution | | Type of work | Duration (hours pw) | No of weeks / Number of activity | Hours in total per term | | Yüz yüze eğitim | 3 | 14 | 42 | | Sınıf dışı çalışma | 5 | 14 | 70 | | Arasınav için hazırlık | 10 | 1 | 10 | | Arasınav | 2 | 1 | 2 | | Ödev | 10 | 1 | 10 | | Dönem sonu sınavı için hazırlık | 15 | 1 | 15 | | Dönem sonu sınavı | 3 | 1 | 3 | | Total work load | | | 152 |
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