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GRADUATE INSTITUTE of HEALTH SCIENCES / DEPARTMENT of MEDICAL BIOCHEMISTRY
Doctorate
Course Catalog
https://www.ktu.edu.tr/sabetibbibiyokimya
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SABE
GRADUATE INSTITUTE of HEALTH SCIENCES / DEPARTMENT of MEDICAL BIOCHEMISTRY / Doctorate
Katalog Ana Sayfa
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TBIO615Lipoproteins2+0+0ECTS:7.5
Year / SemesterFall Semester
Level of CourseThird Cycle
Status Elective
DepartmentDEPARTMENT of MEDICAL BIOCHEMISTRY
Prerequisites and co-requisitesNone
Mode of DeliveryFace to face, Group study
Contact Hours14 weeks - 2 hours of lectures per week
LecturerProf. Dr. Asım ÖREM
Co-LecturerNone
Language of instructionTurkish
Professional practise ( internship ) None
 
The aim of the course:
The course aims to provide the students with a general knowledge on lipoproteins, to enable them to understand the metabolism of lipoproteins, to help them use their knowledge to understand the lipid metabolism disorders and atherosclerosis.
 
Programme OutcomesCTPOTOA
Upon successful completion of the course, the students will be able to :
PO - 1 : Learn clinical importance of lipids1,2,31,3,
PO - 2 : İdentify lipoproteins by classification11,3,
PO - 3 : Learn lipid analyses2,3,51,2,
PO - 4 : learn lipoprotein metabolism1,2,31,3
PO - 5 : learn disorder in lipoprotein metabolism5,81,3
CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), PO : Learning Outcome

 
Contents of the Course
Structure of lipids. Types of lipoproteins.Types of lipids and apolipoproteins in lipoproteins. Apolipoproteins. Digestion and transport of di,etary lipids. Synthesis of lipoproteins. Metabolism of lipoproteins. Cholesterol metabolism and lipoproteins. Lipid metabolism disorders. Ox-LDL and atherosclerosis
 
Course Syllabus
 WeekSubjectRelated Notes / Files
 Week 1srtucture of lipids
 Week 2structure of lipoproteins
 Week 3structural interaction of lipoproteins
 Week 4Apolipoproteinler
 Week 5Absorption of dietery lipids
 Week 6Syntesis of lipoproteins
 Week 7Syntesis of lipoproteins
 Week 8Mid-term exam
 Week 9Endogen and exogen lipoprotein metabolism
 Week 10Intasellüler cholesterol homeostasis
 Week 11Intasellüler cholesterol homeostasis
 Week 12reverse cholesterol transport
 Week 13lipoprotein disorder
 Week 14hyperlipoproteinemia
 Week 15
 Week 16End-of-term exam
 
Textbook / Material
1Vance DE. Biochemistry of Lipids, lipoproteins and Membranes, 5th ed. Elsevier, 2008.
2Mark's medical biochemistry, third ed. Lippincott, 2009.
 
Recommended Reading
 
Method of Assessment
Type of assessmentWeek NoDate

Duration (hours)Weight (%)
Mid-term exam 8 2 30
Homework/Assignment/Term-paper 12 2 20
End-of-term exam 16 2 50
 
Student Work Load and its Distribution
Type of workDuration (hours pw)

No of weeks / Number of activity

Hours in total per term
Yüz yüze eğitim 2 14 28
Sınıf dışı çalışma 2 14 28
Arasınav için hazırlık 2 4 8
Arasınav 2 1 2
Ödev 2 4 8
Dönem sonu sınavı için hazırlık 4 4 16
Dönem sonu sınavı 2 1 2
Total work load92