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TBIO615 | Lipoproteins | 2+0+0 | ECTS:7.5 | Year / Semester | Fall Semester | Level of Course | Third Cycle | Status | Elective | Department | DEPARTMENT of MEDICAL BIOCHEMISTRY | Prerequisites and co-requisites | None | Mode of Delivery | Face to face, Group study | Contact Hours | 14 weeks - 2 hours of lectures per week | Lecturer | Prof. Dr. Asım ÖREM | Co-Lecturer | None | Language of instruction | Turkish | Professional practise ( internship ) | None | | The aim of the course: | The course aims to provide the students with a general knowledge on lipoproteins, to enable them to understand the metabolism of lipoproteins, to help them use their knowledge to understand the lipid metabolism disorders and atherosclerosis. |
Programme Outcomes | CTPO | TOA | Upon successful completion of the course, the students will be able to : | | | PO - 1 : | Learn clinical importance of lipids | 1,2,3 | 1,3, | PO - 2 : | İdentify lipoproteins by classification | 1 | 1,3, | PO - 3 : | Learn lipid analyses | 2,3,5 | 1,2, | PO - 4 : | learn lipoprotein metabolism | 1,2,3 | 1,3 | PO - 5 : | learn disorder in lipoprotein metabolism | 5,8 | 1,3 | CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), PO : Learning Outcome | |
Structure of lipids. Types of lipoproteins.Types of lipids and apolipoproteins in lipoproteins. Apolipoproteins. Digestion and transport of di,etary lipids. Synthesis of lipoproteins. Metabolism of lipoproteins. Cholesterol metabolism and lipoproteins. Lipid metabolism disorders. Ox-LDL and atherosclerosis |
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Course Syllabus | Week | Subject | Related Notes / Files | Week 1 | srtucture of lipids | | Week 2 | structure of lipoproteins | | Week 3 | structural interaction of lipoproteins | | Week 4 | Apolipoproteinler | | Week 5 | Absorption of dietery lipids | | Week 6 | Syntesis of lipoproteins | | Week 7 | Syntesis of lipoproteins | | Week 8 | Mid-term exam | | Week 9 | Endogen and exogen lipoprotein metabolism | | Week 10 | Intasellüler cholesterol homeostasis | | Week 11 | Intasellüler cholesterol homeostasis | | Week 12 | reverse cholesterol transport | | Week 13 | lipoprotein disorder | | Week 14 | hyperlipoproteinemia | | Week 15 | | | Week 16 | End-of-term exam | | |
1 | Vance DE. Biochemistry of Lipids, lipoproteins and Membranes, 5th ed. Elsevier, 2008. | | 2 | Mark's medical biochemistry, third ed. Lippincott, 2009. | | |
Method of Assessment | Type of assessment | Week No | Date | Duration (hours) | Weight (%) | Mid-term exam | 8 | | 2 | 30 | Homework/Assignment/Term-paper | 12 | | 2 | 20 | End-of-term exam | 16 | | 2 | 50 | |
Student Work Load and its Distribution | Type of work | Duration (hours pw) | No of weeks / Number of activity | Hours in total per term | Yüz yüze eğitim | 2 | 14 | 28 | Sınıf dışı çalışma | 2 | 14 | 28 | Arasınav için hazırlık | 2 | 4 | 8 | Arasınav | 2 | 1 | 2 | Ödev | 2 | 4 | 8 | Dönem sonu sınavı için hazırlık | 4 | 4 | 16 | Dönem sonu sınavı | 2 | 1 | 2 | Total work load | | | 92 |
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