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FACULTY of SCIENCE / DEPARTMENT of BIOLOGY

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BIY3004Radiobiology3+0+0ECTS:6
Year / SemesterSpring Semester
Level of CourseFirst Cycle
Status Elective
DepartmentDEPARTMENT of BIOLOGY
Prerequisites and co-requisitesNone
Mode of Delivery
Contact Hours14 weeks - 3 hours of lectures per week
LecturerProf. Dr. Kamil ÇOŞKUNÇELEBİ
Co-LecturerNone
Language of instructionTurkish
Professional practise ( internship ) None
 
The aim of the course:
This course is designed to present an introduction to the general concept of Radiobiology.
 
Learning OutcomesCTPOTOA
Upon successful completion of the course, the students will be able to :
LO - 1 : Describe and explain EMR and PR 1,5,71,5,
LO - 2 : Explain the effect of EMR and PR on human cells, tissue and organs1,5,71,5,
LO - 3 : Summaries the importance and dangerous of Radiation on Human body1,5,71,5,
LO - 4 : Summaries the types of Radiations1,5,71,5,
CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), LO : Learning Outcome

 
Contents of the Course
History of radiobiology, radiobiological terms and concepts, radiation and the effect mechanism of radiation, radiation types, absorption of radiation, radicals, radiation units, detectors, effects of radiation on bio-macromolecules, cells, tissues, organs and organism (especially human) . Detection of radiation level and types of protection from several kind of radiation.
 
Course Syllabus
 WeekSubjectRelated Notes / Files
 Week 1Basic term and its explanations
 Week 2Ionization Radiation
 Week 3Linear energy tranfery (LET) and Relative Biological Effect (RBE)
 Week 4Effect of IR on nucleic acids
 Week 5Effects of IR on subcellular level
 Week 6Kinetics of cell populations
 Week 7Effect of IR on cell growth
 Week 8Negative effects caused by IR in the cell and its restoration process in the cell
 Week 9Mid-term exam
 Week 10Radicals
 Week 11The effect of IR on cell cyclus
 Week 12Radiosensitivors
 Week 13Radioprotectors
 Week 14Effects of IR on tissue and organs
 Week 15The late effect of IR: genetic and carsinogen effects of IR
 Week 16End-of-term exam
 
Textbook / Material
1Temel Radyobiyoloji, Haliç Üniversitesi Yayınları, İstanbul, Atila Özalpan, 2002.
 
Recommended Reading
1Introduction to Radiaobiology. Willey and Sons Ltd., London, 2000.
 
Method of Assessment
Type of assessmentWeek NoDate

Duration (hours)Weight (%)
Mid-term exam 9 24/04/2024 1 35
Homework/Assignment/Term-paper Seminer 02,09/06/2024 15
End-of-term exam 16 13/06/2024 1 50
 
Student Work Load and its Distribution
Type of workDuration (hours pw)

No of weeks / Number of activity

Hours in total per term
Yüz yüze eğitim 3 14 42
Sınıf dışı çalışma 2.5 14 35
Arasınav için hazırlık 2.5 8 20
Arasınav 1.5 5 7.5
Ödev 1 14 14
Dönem sonu sınavı için hazırlık 2 10 20
Dönem sonu sınavı 1.5 1 1.5
Diğer 1 2 20 40
Total work load180