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| MBGL7021 | Epigenetic Memory in Plants | 3+0+0 | ECTS:7.5 | | Year / Semester | Spring Semester | | Level of Course | Third Cycle | | Status | Elective | | Department | DEPARTMENT of MOLECULAR BIOLOGY and GENETICS | | Prerequisites and co-requisites | None | | Mode of Delivery | | | Contact Hours | 14 weeks - 3 hours of lectures per week | | Lecturer | Prof. Dr. Aykut SAĞLAM | | Co-Lecturer | | | Language of instruction | Turkish | | Professional practise ( internship ) | None | | | | The aim of the course: | | Epigenetics refers to hereditary changes in gene expression without changes in the DNA sequence. Epigenetic mechanisms include covalent modifications of DNA and histones that affect the transcriptional activity of chromatin. Epigenetic mechanisms are also associated with 'cellular memory'. In this course, selected epigenetic memory samples in plants will be reviewed and related molecular mechanisms will be discussed in detail. |
| Programme Outcomes | CTPO | TOA | | Upon successful completion of the course, the students will be able to : | | | | PO - 1 : | have information about epigenetic changes. | 1,2,3,7 | | | PO - 2 : | discuss molecular mechanisms related to epigenetics in detail. | 1,2,3,7 | | | PO - 3 : | learn covalent modifications of DNA and histones | 1,2,3,7 | | | PO - 4 : | review selected epigenetic memory samples in plants. | 1,2,3,7 | | | CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), PO : Learning Outcome | | |
| Course content; basic principles of epigenetics, epigenetic mechanisms, plant epigenetics, biotic stress and epigenetic-related processes in plants, abiotic stress and epigenetic-related processes in plants, epigenetic memory and phytohormones, priming, epigenetic memory and priming, epigenetic memory: applications in arabidopsis |
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| Course Syllabus | | Week | Subject | Related Notes / Files | | Week 1 | Epigenetics: Introduction | | | Week 2 | Epigenetic Mechanisms | | | Week 3 | Plant Epigenetics | | | Week 4 | Processes Related to Biotic Stress and Epigenetics in Plants | | | Week 5 | Examples of Biotic Stress and Epigenetics in Plants | | | Week 6 | Abiotic Stress and Epigenetic Related Processes in Plants | | | Week 7 | Examples of Abiotic Stress and Epigenetics in Plants | | | Week 8 | Epigenetic Memory and Phytohormones | | | Week 9 | Mid-term exam | | | Week 10 | Epigenetic Memory and Transcription factors | | | Week 11 | Priming | | | Week 12 | Epigenetic Memory and Priming | | | Week 13 | Epigenetic Memory: Applications in Arabidopsis | | | Week 14 | Epigenetic Memory: Applications in Arabidopsis | | | Week 15 | Epigenetic Memory: Applications in Arabidopsis | | | Week 16 | Final exam | | | |
| 1 | Iwasaki M, Paszkowski J (2014) Epigenetic memory in plants. EMBO J 33:1987?1998. https://doi.org/10.15252/embj.201488883 | | | 2 | Ders notları | | | |
| Method of Assessment | | Type of assessment | Week No | Date | Duration (hours) | Weight (%) | | Mid-term exam | 9 | | 3 | 30 | | Oral exam | 11 | | 2 | 20 | | End-of-term exam | 16 | | 3 | 50 | | |
| Student Work Load and its Distribution | | Type of work | Duration (hours pw) | No of weeks / Number of activity | Hours in total per term | | Yüz yüze eğitim | 3 | 14 | 42 | | Sınıf dışı çalışma | 3 | 14 | 42 | | Arasınav için hazırlık | 3 | 8 | 24 | | Arasınav | 2 | 1 | 2 | | Ödev | 1 | 11 | 11 | | Dönem sonu sınavı için hazırlık | 3 | 14 | 42 | | Dönem sonu sınavı | 2 | 14 | 28 | | Total work load | | | 191 |
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