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| BTBI7218 | Diagnosis and Treatment of Bacterial Fish Diseases | 3+0+0 | ECTS:7.5 | | Year / Semester | Fall Semester | | Level of Course | Third Cycle | | Status | Elective | | Department | DEPARTMENT of FISHERIES TECHNOLOGY ENGINEERING | | Prerequisites and co-requisites | None | | Mode of Delivery | | | Contact Hours | 14 weeks - 3 hours of lectures per week | | Lecturer | Prof. Dr. İlhan ALTINOK | | Co-Lecturer | | | Language of instruction | | | Professional practise ( internship ) | None | | | | The aim of the course: | | The primary aim of this course is to provide students with advanced theoretical knowledge and practical skills regarding the identification, diagnosis, and management of bacterial pathogens that cause economic losses in aquaculture. The course aims to teach disease not merely as the presence of a pathogen but within the framework of Snieszko's Disease Triad (Host-Pathogen-Environment), enabling students to analyze environmental stress factors. Furthermore, it intends to instruct on strategies for mitigating antimicrobial resistance (AMR) risks, administering medication in compliance with Turkish and EU regulations, monitoring residues (MRL), and applying preventive medicine strategies such as vaccination. |
| Programme Outcomes | CTPO | TOA | | Upon successful completion of the course, the students will be able to : | | | | PO - 1 : | Students will be able to identify and classify major bacterial pathogens (Gram-negative and Gram-positive) affecting cultured fish based on clinical signs and laboratory data. | 1 - 2 - 3 - 4 - 5 | 1,3,4, | | PO - 2 : | Students will master the specialized terminology of fish pathology (e.g., exophthalmia, ascites, furuncle) and use it effectively in professional communication. | | 1,2,3, | | PO - 3 : | Students will demonstrate proficiency in performing diagnostic necropsies, aseptic sampling from the kidney/spleen, and executing standard bacterial culture techniques. | | 1,2,4, | | PO - 4 : | Öğrenciler, yasal arınma sürelerine uyarak oral ve banyo uygulamaları için dozaj hesaplamaları yapabilecek ve uygun antimikrobiyal tedavi protokolleri tasarlayabilecektir. | | 1,2,3,5, | | PO - 5 : | Öğrenciler, antimikrobiyal direnç (AMR) riskini eleştirel bir şekilde analiz edecek ve birincil koruyucu önlemler olarak biyogüvenlik ve aşılama stratejilerini uygulayacaktır. | | 1,2,3,5, | | PO - 6 : | Öğrenciler, yasaklı maddeler (örn. Nitrofuranlar) ve maksimum kalıntı limitleri (MRL) ile ilgili Türk ve AB yönetmeliklerini yorumlayacak ve uygulayacaktır. | | 1,3,5, | | CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), PO : Learning Outcome | | |
| This course covers the etiology, epidemiology, and pathology of major Gram-negative (Aeromonas, Vibrio, Yersinia, Flavobacterium) and Gram-positive (Streptococcus, Lactococcus, Renibacterium) bacterial agents encountered in aquaculture. The content details modern diagnostic methods such as fish necropsy, aseptic sampling, bacterial culture, and PCR. Additionally, it comprehensively addresses therapeutic protocols, including antimicrobial pharmacology, dosage calculations, banned substances (e.g., Nitrofurans), and legal withdrawal periods, as well as prophylactic strategies involving biosecurity and autogenous vaccine applications. |
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| Course Syllabus | | Week | Subject | Related Notes / Files | | Week 1 | Introduction to Fish Bacteriology, Stress, and Host-Pathogen Interactions | | | Week 2 | Clinical Examination, Necropsy, and Aseptic Sampling Techniques | | | Week 3 | Laboratory Identification: Culture vs. Molecular Methods | | | Week 4 | The Aeromonads: Furunculosis and Motile Aeromonas Septicemia | | | Week 5 | Vibrionaceae and Photobacteriosis | | | Week 6 | Enterobacteriaceae: Yersiniosis and Edwardsiellosis | | | Week 7 | Flavobacteriaceae: Columnaris, Cold Water Disease, and Tenacibaculosis | | | Week 8 | Midterm Examination and Laboratory Review | | | Week 9 | Gram-Positive Cocci: Streptococcosis and Lactococcosis | | | Week 10 | Chronic Granulomatous Diseases: BKD and Mycobacteriosis | | | Week 11 | Rickettsia-like and Fastidious Pathogens | | | Week 12 | Emerging Bacterial Threats | | | Week 13 | Antimicrobial Therapy, Regulations, and Banned Substances | | | Week 14 | Midterm Examination (Homework) | | | Week 15 | Antimicrobial Therapy, Regulations, and Banned Substances | | | Week 16 | Vaccination Strategies and Biosecurity | | | |
| 1 | Austin, B., & Austin, D. A. (2016). Bacterial fish pathogens: Disease of farmed and wild fish (6. baskı). Springer.
Bacterial Diseases of Fish - Inglis, Roberts, and Bromage.
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| 1 | Noga, E. J. (2010). Fish disease: Diagnosis and treatment (2. baskı). Wiley-Blackwell. | | | |
| Method of Assessment | | Type of assessment | Week No | Date | Duration (hours) | Weight (%) | | Mid-term exam | 8 | 21/11/2025 | 02 | 30 | | Presentation | 14 | 26/12/2025 | 01 | 20 | | End-of-term exam | 16 | 16/01/2025 | | 50 | | |
| Student Work Load and its Distribution | | Type of work | Duration (hours pw) | No of weeks / Number of activity | Hours in total per term | | Yüz yüze eğitim | 2 | 14 | 28 | | Laboratuar çalışması | 1 | 8 | 8 | | Arasınav için hazırlık | 2 | 7 | 14 | | Arasınav | 2 | 1 | 2 | | Uygulama | 1 | 4 | 4 | | Ödev | 1 | 3 | 3 | | Dönem sonu sınavı için hazırlık | 2 | 8 | 16 | | Dönem sonu sınavı | 2 | 1 | 2 | | Total work load | | | 77 |
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