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| EAK6004 | Drug Analysis in Biological Liquids | 3+0+0 | ECTS:7.5 | | Year / Semester | Fall Semester | | Level of Course | Third Cycle | | Status | Elective | | Department | ANALYTICAL CHEMISTRY IN PHARMACY | | Prerequisites and co-requisites | None | | Mode of Delivery | | | Contact Hours | 14 weeks - 3 hours of lectures per week | | Lecturer | -- | | Co-Lecturer | | | Language of instruction | Turkish | | Professional practise ( internship ) | None | | | | The aim of the course: | | To learn how to make drug analysis in biological samples, methods used. |
| Programme Outcomes | CTPO | TOA | | Upon successful completion of the course, the students will be able to : | | | | PO - 1 : | Evaluate the importance of drug analysis in biological fluids. | 1,3,9,10 | 1,3, | | PO - 2 : | Discuss the problems encountered in the process of biological samples. | 1,3,10,11 | 1,3, | | PO - 3 : | Analyze drugs with biological samples. | 1,3,9,10 | 1,3, | | PO - 4 : | Can provide social information and social activities in cases requiring drug analysis. | 1,3,9,10 | 1,3, | | CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), PO : Learning Outcome | | |
| Biological samples, storage conditions of biological samples, extraction processes, drying processes, contamination sources and errors, quantification methods, method selection, evaluation of results. |
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| Course Syllabus | | Week | Subject | Related Notes / Files | | Week 1 | Sample preparation techniques from biological matrices | | | Week 2 | Precipitation, ultrafiltration, extraction | | | Week 3 | Stability and extraction of drugs in biological environment | | | Week 4 | Extraction techniques: liquid-liquid extraction, solid phase extraction | | | Week 5 | Instrumental techniques used in biological analysis | | | Week 6 | Instrumental techniques used in biological analysis | | | Week 7 | Instrumental techniques used in biological analysis | | | Week 8 | Instrumental techniques used in biological analysis | | | Week 9 | Midterm exam | | | Week 10 | Validation of biological analysis methods | | | Week 11 | Validation of biological analysis methods | | | Week 12 | Innovations in biological analysis methods | | | Week 13 | Examples of drug analysis from biological samples in literature | | | Week 14 | Examples of drug analysis from biological samples in literature | | | Week 15 | Examples of drug analysis from biological samples in literature | | | Week 16 | Final Examination | | | |
| 1 | Kütüphane, Abone Veri Tabanları | | | |
| Method of Assessment | | Type of assessment | Week No | Date | Duration (hours) | Weight (%) | | Mid-term exam | 9 | 25/11/2023 | 2 | 30 | | In-term studies (second mid-term exam) | 14 | 10/01/2024 | 2 | 20 | | End-of-term exam | 16 | 15/01/2025 | 2 | 50 | | |
| Student Work Load and its Distribution | | Type of work | Duration (hours pw) | No of weeks / Number of activity | Hours in total per term | | Yüz yüze eğitim | 3 | 14 | 42 | | Arasınav için hazırlık | 7 | 8 | 56 | | Arasınav | 2 | 1 | 2 | | Dönem sonu sınavı için hazırlık | 6 | 15 | 90 | | Dönem sonu sınavı | 2 | 1 | 2 | | Total work load | | | 192 |
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