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| BIY5100 | Molecular Genetics | 3+0+0 | ECTS:7.5 | | Year / Semester | Fall Semester | | Level of Course | Second Cycle | | Status | Elective | | Department | DEPARTMENT of BIOLOGY | | Prerequisites and co-requisites | None | | Mode of Delivery | Face to face | | Contact Hours | 14 weeks - 3 hours of lectures per week | | Lecturer | Prof. Dr. Sabriye ÇANAKÇI | | Co-Lecturer | Prof. Dr. Ali Osman BELDUZ | | Language of instruction | Turkish | | Professional practise ( internship ) | None | | | | The aim of the course: | | Increasing the students' knowledge on molecular biology of the gene and gene expression in procaryotes and eucaryotes in a relative manner and prepare them for a graduate study. |
| Programme Outcomes | CTPO | TOA | | Upon successful completion of the course, the students will be able to : | | | | PO - 1 : | describe the three ways bacteria can exchange genes as well as understand restriction endonucleases.
| 1,2,7 | 1,5 | | PO - 2 : | understand the molecular structure of eukaryotic chromosomes and repetitive DNA
| 1,2,7 | 1,5 | | PO - 3 : | understand methylation and its function in chromosome inactivation and gene imprinting
| 1,2,7 | 1,5 | | PO - 4 : | describe eukaryotic posttranscriptional processing, initiation of translation and posttranslational modifications
| 1,2,7 | 1,5 | | PO - 5 : | contrast and compare the molecular genetics (structure and control) of prokaryote versus eukaryote genes
| 1,2,7 | 1,5 | | CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), PO : Learning Outcome | | |
| Molecular aspects of prokaryotic and eukaryotic genetics; chromosome structures, mutations, transfer of genetic information, DNA replication, recombination, transcription, translation, and regulation of gene activity. |
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| Course Syllabus | | Week | Subject | Related Notes / Files | | Week 1 | Nucleic acid structure and function | | | Week 2 | Nucleic acid structure and function | | | Week 3 | Mutation, Variation and Repair | | | Week 4 | Regulation of Gene Expression | | | Week 5 | Regulation of Gene Expression | | | Week 6 | Gene exchange in prokaryote | | | Week 7 | Gene Transfer in Eukaryote | | | Week 8 | Movable Genes | | | Week 9 | Mid-term exam | | | Week 10 | Control of Microbial growht | | | Week 11 | Student Seninar | | | Week 12 | Student Seminar | | | Week 13 | Metilation and inprinting | | | Week 14 | Genetic analysis | | | Week 15 | Genetic analysis | | | Week 16 | End-of-term exam | | | |
| 1 | Klug, W.S., Cummings, M.R., Spencer, C.A. Çeviri Editörleri : Öner, C., Sümer, S., Öner, R., Öğüş, A., Açık, A. 2009, Genetik, Palme Yayıncılık, Ankara. | | | |
| 1 | Dale, J.W. 1998, Molecular Genetics of Bacteria, John Wiley and Sons, Chichester | | | 2 | Madigan, M.T., Martinko, J.M., Çeviri Editötü: Çökmüş, C. 2010, Brook Mikroorganizmaların Biyolojisi, Palme Yayıncılık, Ankara | | | |
| Method of Assessment | | Type of assessment | Week No | Date | Duration (hours) | Weight (%) | | Mid-term exam | 9 | 25-11-2023 | 1 | 30 | | Presentation | 13 | 14/12/2023 | 1 | 20 | | End-of-term exam | 16 | 19/01/2024 | 1 | 50 | | |
| Student Work Load and its Distribution | | Type of work | Duration (hours pw) | No of weeks / Number of activity | Hours in total per term | | Yüz yüze eğitim | 3 | 14 | 42 | | Sınıf dışı çalışma | 3 | 14 | 42 | | Laboratuar çalışması | 0 | 0 | 0 | | Arasınav için hazırlık | 40 | 1 | 40 | | Arasınav | 1 | 1 | 1 | | Uygulama | 0 | 0 | 0 | | Klinik Uygulama | 0 | 0 | 0 | | Ödev | 29 | 1 | 29 | | Proje | 0 | 0 | 0 | | Kısa sınav | 0 | 0 | 0 | | Dönem sonu sınavı için hazırlık | 40 | 1 | 40 | | Dönem sonu sınavı | 1 | 1 | 1 | | Diğer 1 | 30 | 1 | 30 | | Diğer 2 | 0 | 0 | 0 | | Total work load | | | 225 |
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