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| DIS 343 | Pharmacology | 2+0+0 | ECTS:4 | | Year / Semester | Fall Semester | | Level of Course | Second Cycle | | Status | Compulsory | | Department | DEPARTMENT of DENTISTRY | | Prerequisites and co-requisites | None | | Mode of Delivery | Face to face, Group study | | Contact Hours | 14 weeks - 2 hours of lectures per week | | Lecturer | Prof. Dr. Nuri İhsan KALYONCU | | Co-Lecturer | Prof. Dr. Ersin YARIŞ, Prof. Dr. Nuri İhsan KALYONCU, Assoc. Prof. Dr. Sabri Murat KESİM. | | Language of instruction | Turkish | | Professional practise ( internship ) | None | | | | The aim of the course: | | The course aims to provide students general knowledge about the basic principles of pharmacology, and give information about the drugs used in the treatment of different diseases. |
| Learning Outcomes | CTPO | TOA | | Upon successful completion of the course, the students will be able to : | | | | LO - 1 : | describe and comment on the absorption, bioavailability, distribution and elimination of the drugs, and the drug-receptor interaction.
| 1,2,7 | 1, | | LO - 2 : | comment on the physiology of autonomic nervous system, and to classify the drugs used in the therapy of the diseases related with the autonomic nervous system.
| 1,2,7 | 1, | | LO - 3 : | describe and comment on the drugs used in cardiovascular diseases.
| 1,2,7 | 1, | | LO - 4 : | comment on the physiology of central nervous system, and to classify the drugs used in the therapy of the diseases related with the central nervous system.
| 1,2,7 | 1, | | LO - 5 : | describe and comment on the general principles and properties of chemotherapeutics.
| 1,2,7 | 1, | | CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), LO : Learning Outcome | | |
| General knowledge about the physiopathological mechanisms and the drugs used in the treatment of the diseases. Basic principles of PharmacologyRoutes of drug administrationThe pharmaceutical forms of drugsAbsorption and distribution of drugs Metabolism and elimination of drugs Receptors and drug-receptor interactionDose-concentration-effect interaction Mechanisms of drug action Factors affecting the drug actionInteraction between the drugsToxic effects of drugsDrug allergiesThe teratogenic, mutagenic and carcinogenic effects of drugsProstaglandins and leukotrienesOther autacoidsHistamine and antihistaminic drugs Serotonin and serotonin antagonist drugs Angiotensine and antagonist drugsIntroduction to Autonomic Nervous System Pharmacology Parasympathomimetic-Parasympatholytic drugs Sympathomimetic-Sympatholytic drugs Drugs used to treat congestive heart failure Drugs used to treat angina pectoris Antihypertensive drugs. Drugs used in disorders of coagulation Drugs used to treat arrhythmiasHypolipidemic drugsIntroduction to Central Nervous System Pharmacology Drug addictionLocal anesthetics General anesthetics Sedatives-hypnoticsAlcoholsAntidepressant drugsAnticonvulsant drugsNeuroleptic drugsAntiparkinson drugsNon-steroidal anti-inflammatory analgesicsNarcotic analgesics Drugs used to treat migraine Principles of Antimicrobial Drug UsePenicillinCephalosporinesOther Beta- Lactam antibioticsChloramphenicolsMacrolides TetracyclinesAminoglycosides SulfonamidesFloroquinolonesDrug used to treat tuberculosis and lepraeAntianerobic drugsMiscellaneous antibiotics Antiseptics and dezenfektanlar Antiviral drugs and drugs used to treat AIDS General principles of drug poisoning Prescription
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| Course Syllabus | | Week | Subject | Related Notes / Files | | Week 1 | Introduction
Pharmaceutical forms of drugs | | | Week 2 | Drug applications
Mechanisms of drug action | | | Week 3 | Absorbtion and distribution of drugs | | | Week 4 | Biotransformation and elimination of drugs I | | | Week 5 | Biotransformation and elimination of drugs II | | | Week 6 | Factors of changing the action of drugs
İnteractions between drugs | | | Week 7 | Receptors and drug-receptor interaction
Dose-concentration-action interaction | | | Week 8 | Toxic actions of drugs; drug allergies | | | Week 9 | Tetratogenic, mutagenic and carcinogenic actions of drugs | | | Week 10 | Serotonin and antagonists of serotonin
Histamin and antihistaminics | | | Week 11 | Prostaglandins and leukotriens
Angiotensin and its antagonists | | | Week 12 | Introduction to Autonomic Nervous System | | | Week 13 | Cempatomimetic drugs | | | Week 14 | Cempatolitic drugs | | | Week 15 | midterm exam | | | Week 16 | Parasempatomimetic drugs; Parasempatolitic drugs | | | Week 17 | Antihypertensive drugs | | | |
| 1 | Kayaalp OS. 2006; Rasyonel Tedavi Yönünden Tıbbi Farmakoloji,Türkiye | | | |
| Method of Assessment | | Type of assessment | Week No | Date | Duration (hours) | Weight (%) | | Mid-term exam | 15
30 | 26/12/2023
22/05/2024 | 1
1 | 50 | | End-of-term exam | 33 | 28/06/2024 | 1 | 50 | | |
| Student Work Load and its Distribution | | Type of work | Duration (hours pw) | No of weeks / Number of activity | Hours in total per term | | Yüz yüze eğitim | 2 | 14 | 28 | | Sınıf dışı çalışma | 4 | 14 | 56 | | Arasınav için hazırlık | 4 | 4 | 16 | | Arasınav | 0 | 0 | 0 | | Dönem sonu sınavı | 0 | 0 | 0 | | Total work load | | | 100 |
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